CHEMBL3084502


SMILES O[C@@]1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2Cc1c[nH]c2ccccc12
InChIKey AXPWNFAVTPIWHV-HATOLVCRSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.52 5.52 5.52 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.91 5.91 5.91 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.6 7.71 7.81 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.32 5.32 5.32 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.79 7.13 7.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 7.91 7.91 7.91 ChEMBL
D2 DRD2 Human Dopamine A pIC50 7.32 7.32 7.32 ChEMBL