CHEMBL3084512


SMILES O[C@]1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2Cc1csc2ccccc12
InChIKey PRWXOHHRHWZNOG-NGRWLJPCSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 383.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.85 6.85 6.85 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.52 5.52 5.52 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.44 8.44 8.44 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.15 7.15 7.15 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.76 5.76 5.76 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.89 7.89 7.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 8.38 8.38 8.38 ChEMBL
D2 DRD2 Human Dopamine A pIC50 7.58 7.58 7.58 ChEMBL