GPCRdb

CHEMBL325516

SMILES	O=C(OCCc1ccc(F)cc1)N1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1
InChIKey	NEUFWHZAVWYYSZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors	3
Hydrogen bond donors	0
Rotatable bonds	9
Molecular weight (Da)	496.2

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source
GTP No matches found	Uniprot No matches found	Species No matches found	Family No matches found	Class No matches found	Type No matches found	Min	Avg	Max	Database No matches found
No data available in table

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Receptor					Activity				Source
GTP No matches found	Uniprot No matches found	Species No matches found	Family No matches found	Class No matches found	Type No matches found	Min	Avg	Max	Database No matches found
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pIC50	5.94	5.94	5.94	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pIC50	5.97	5.97	5.97	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pIC50	5.46	5.46	5.46	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pIC50	5.82	5.82	5.82	ChEMBL
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pIC50	6.14	6.14	6.14	ChEMBL
A₃	AA3R	Human	Adenosine	A	pIC50	5.38	5.38	5.38	ChEMBL
D₂	DRD2	Human	Dopamine	A	pIC50	5.58	5.58	5.58	ChEMBL
D₃	DRD3	Human	Dopamine	A	pIC50	6.34	6.34	6.34	ChEMBL
D₄	DRD4	Human	Dopamine	A	pIC50	6.47	6.47	6.47	ChEMBL
D₅	DRD5	Human	Dopamine	A	pIC50	5.81	5.81	5.81	ChEMBL
H₁	HRH1	Human	Histamine	A	pIC50	5.89	5.89	5.89	ChEMBL
H₂	HRH2	Human	Histamine	A	pIC50	5.9	5.9	5.9	ChEMBL
κ	OPRK	Human	Opioid	A	pIC50	5.37	5.37	5.37	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	5.4	5.4	5.4	ChEMBL

Showing 1 to 14 of 14 entries