CHEMBL3264441


SMILES CCOC(=O)C(CN1CC[C@@](C)(c2cccc(O)c2)[C@@H](C)C1)OC(=O)[C@H]1Cc2ccc(O)cc2CN1
InChIKey HPYASOWAVYTFJW-XTNINKNLSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 496.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKd 8.62 8.62 8.62 ChEMBL
δ OPRD Human Opioid A pKi 5.97 5.97 5.97 ChEMBL
κ OPRK Human Opioid A pKi 8.62 8.69 8.76 ChEMBL
μ OPRM Human Opioid A pKi 7.58 7.58 7.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database