CHEMBL310867


SMILES CCCN(CCC)[C@H]1CCc2nn3ccccc3c2C1
InChIKey PWWITWFCENNJEP-AWEZNQCLSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 271.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 7.75 7.75 7.75 ChEMBL
D2 DRD2 Bovine Dopamine A pKi 8.07 8.07 8.07 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.3 7.3 7.3 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.27 9.27 9.27 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.6 5.6 5.6 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.07 7.27 7.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pEC50 7.33 7.56 7.8 ChEMBL
D4 DRD4 Human Dopamine A pEC50 6.37 6.37 6.37 ChEMBL
D3 DRD3 Human Dopamine A pEC50 8.55 8.55 8.55 ChEMBL