CHEMBL313320


SMILES COc1ccc(Br)cc1C1=N[C@@H](CN2CCN(c3ccccc3)CC2)CO1
InChIKey LKDKZDZBTSCLCY-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 429.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.05 5.38 5.7 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.8 6.11 6.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.28 5.64 6.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.66 6.27 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database