Chembl3323521
Chemical Properties
| SMILES | CCC(=O)N1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)C2C(N3CCCC3)CCCC21 |
| Hydrogen bond acceptors | 3 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 4 |
| Molecular weight | 451.2 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | VEGAAHPOHDZSNL-UHFFFAOYSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| κ | OPRK | Guinea pig | Opioid | A | pKi | 6.36 | 6.97 | 7.58 | ChEMBL |
| κ | OPRK | Human | Opioid | A | pEC50 | 6.22 | 6.22 | 6.22 | ChEMBL |
| μ | OPRM | Human | Opioid | A | pKi | 5.48 | 5.48 | 5.48 | ChEMBL |