CHEMBL315223


SMILES Cn1ccc2c3c(ccc21)N(C(=O)Nc1cccnc1)CC3
InChIKey WWORPZXUCHHSOT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 292.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 7.75 7.78 7.8 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.18 7.18 7.18 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.54 5.54 5.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database