CHEMBL321557


SMILES COc1cccc2c1CCCC2CCCN1CCN(c2ccc(Cl)cc2)CC1
InChIKey TWAJXJHCRRIGAN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 398.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.98 6.98 6.98 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.47 5.47 5.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database