CHEMBL321761


SMILES CC(C)N(C(=O)CN1C(=O)C(NC(=O)Nc2ccccc2)C(=O)N(c2ccccc2)c2ccccc21)c1ccccc1
InChIKey ITMJPTIFWLPIOL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 561.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Human Cholecystokinin A pKi 7.6 7.6 7.6 ChEMBL
CCK1 CCKAR Human Cholecystokinin A pKi 7.3 7.3 7.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK1 CCKAR Guinea pig Cholecystokinin A pEC50 5.9 5.9 5.9 ChEMBL
CCK1 CCKAR Rat Cholecystokinin A pIC50 6.6 6.6 6.6 ChEMBL
CCK2 GASR Human Cholecystokinin A pIC50 7.6 7.61 7.62 ChEMBL
CCK1 CCKAR Human Cholecystokinin A pIC50 7.26 7.29 7.3 ChEMBL