Chembl3392247

Chemical Properties

SMILES COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1cccc([N+](=O)[O-])c1
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight 608.3

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey ZCZTWAKGRMWSEI-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.63 6.63 6.63 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 5.91 5.91 5.91 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.25 6.25 6.25 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 9.4 9.4 9.4 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.81 5.81 5.81 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.37 6.37 6.37 ChEMBL