CHEMBL322802
SMILES | COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C |
InChIKey | XNUNIHJOMFCFRQ-LIRRHRJNSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 2 |
Rotatable bonds | 5 |
Molecular weight (Da) | 387.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D1 | DRD1 | Bovine | Dopamine | A | pKi | 4.72 | 4.94 | 5.15 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 7.46 | 7.79 | 8.13 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 5.66 | 6.68 | 7.7 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.33 | 7.25 | 8.13 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |