Chembl3398475

Chemical Properties

SMILES Cc1ccc(-n2nccn2)c(C(=O)NCCn2ccc(-c3ccc(F)cn3)n2)c1
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight 391.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey NAHUIASVYYTMTJ-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pIC50 6.92 6.92 6.92 ChEMBL
OX2 OX2R Human Orexin A pIC50 6.7 6.7 6.7 ChEMBL