CHEMBL325818


SMILES COc1c(C(=O)NC[C@@H]2CCN(Cc3ccccc3)C2)cc(Br)c2ccccc12
InChIKey CNAWUGXPLJMOSN-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 452.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.54 5.61 5.68 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.89 7.0 7.11 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.0 6.2 6.39 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.89 6.13 6.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database