CHEMBL3403332


SMILES O=S(=O)(Nc1cc2c(c3ccccc13)OC1(N3CCOCC3)CCCCC21)c1ccccc1
InChIKey HFLXQNRSNZOBAL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 464.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.7 4.7 4.7 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.01 5.01 5.01 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.69 4.69 4.69 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.47 4.47 4.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database