CHEMBL326263


SMILES N#Cc1ccc(CCOC(=O)N2CCN(CCCC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1
InChIKey JJKPSOUEWPDPFS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 503.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pIC50 5.47 5.47 5.47 ChEMBL
D5 DRD5 Human Dopamine A pIC50 6.0 6.0 6.0 ChEMBL
H2 HRH2 Human Histamine A pIC50 5.99 5.99 5.99 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.84 5.84 5.84 ChEMBL
H1 HRH1 Human Histamine A pIC50 6.1 6.1 6.1 ChEMBL
D4 DRD4 Human Dopamine A pIC50 6.11 6.11 6.11 ChEMBL
D1 DRD1 Human Dopamine A pIC50 5.95 5.95 5.95 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 5.64 5.64 5.64 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.71 6.71 6.71 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.15 6.15 6.15 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 5.99 5.99 5.99 ChEMBL
A3 AA3R Human Adenosine A pIC50 5.46 5.46 5.46 ChEMBL
μ OPRM Human Opioid A pIC50 5.83 5.83 5.83 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.65 5.65 5.65 ChEMBL