CHEMBL105091


SMILES CN1CCC(c2c[nH]c3ccc(NC(=O)c4ccco4)nc23)CC1
InChIKey YLMDJSLIPJEWKV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 324.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.96 5.96 5.96 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.03 6.03 6.03 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.25 6.25 6.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pEC50 7.96 7.96 7.96 ChEMBL