CHEMBL3287390


SMILES Clc1cccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c1Cl
InChIKey QNWQLJBICCQPMP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 418.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.89 6.89 6.89 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.15 8.15 8.15 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.41 7.44 7.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 7.18 7.18 7.18 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.75 6.75 6.75 ChEMBL