CHEMBL3289642


SMILES O=C1c2ccc(F)cc2CC1CCN1CCN(c2ccc(Cl)cc2)CC1
InChIKey JLUQWCZYPJKNMK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 372.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.21 8.21 8.21 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.19 6.19 6.19 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.6 5.61 5.61 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.81 5.81 5.81 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database