CHEMBL3289645


SMILES FC(F)(F)c1ccc(OCCCN2CCN(c3ccccn3)CC2)cc1
InChIKey APDUBUJHUYQKMX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 365.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.9 7.91 7.92 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.63 5.63 5.63 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.45 6.45 6.45 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.96 5.96 5.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database