CHEMBL3289648


SMILES Cc1ccc(N2CCN(CCCCc3ccc(F)cc3)CC2)nc1
InChIKey KERODJLVCVZLOA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 327.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.49 5.5 5.5 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.2 7.21 7.22 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.64 7.64 7.64 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.79 5.79 5.79 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.8 6.8 6.81 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.86 6.86 6.86 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.03 7.04 7.04 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.7 5.71 5.73 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.28 6.28 6.28 ChEMBL
D4 DRD4 Rat Dopamine A pKi 7.64 7.64 7.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database