CHEMBL3318846


SMILES O=C(CCN1CCN(CCC(=O)OC2(c3ccc(Cl)cc3)CCN(CCCC(=O)c3ccc(F)cc3)CC2)CC1)OC1(c2ccc(Cl)cc2)CCN(CCCC(=O)c2ccc(F)cc2)CC1
InChIKey BXOPFJXHIDYFEL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 0
Rotatable bonds 20
Molecular weight (Da) 944.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 8.6 8.78 8.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.02 8.02 8.02 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.48 7.48 7.48 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.44 6.44 6.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database