CHEMBL357684


SMILES COc1ccccc1N1CCN(CCCNC(=O)c2cc3ccccn3n2)CC1
InChIKey UMEFKDHFJIKPGP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 393.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 5.92 5.92 5.92 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.39 7.39 7.39 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.25 6.25 6.25 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.19 6.19 6.19 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.01 6.25 6.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database