CHEMBL3349197


SMILES COC(=O)N1[C@H]2CC[C@@H]1C[C@](O)(C#Cc1cccc(C)c1)C2
InChIKey SONLNLJEFBMKGV-ALXJQNPVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 299.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.15 7.15 7.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.32 7.32 7.32 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.29 7.29 7.29 ChEMBL