CHEMBL3613879


SMILES Clc1cccc(N2CCN(CCCc3cn(-c4ccn5nccc5c4)nn3)CC2)c1Cl
InChIKey ILRFVZOWNPFKOR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 455.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.96 6.96 6.96 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.38 7.38 7.38 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.28 8.28 8.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.07 8.07 8.07 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.89 7.08 7.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 5.95 5.95 5.95 ChEMBL