Chembl361883

Chemical Properties

SMILES COc1ccc(-n2nc(Sc3ccc(Cl)cc3)cc(CC[C@@H](C)NC(=O)[C@H]3CCNC[C@@H]3c3ccc(F)cc3)c2=O)cc1
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight 620.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey VLQGURFNWDTOFC-HAQLSYKPSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pIC50 5.92 5.92 5.92 ChEMBL
MC4 MC4R Human Melanocortin A pIC50 7.18 7.18 7.18 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 6.96 6.96 6.96 ChEMBL