Chembl361883
Chemical Properties
| SMILES | COc1ccc(-n2nc(Sc3ccc(Cl)cc3)cc(CC[C@@H](C)NC(=O)[C@H]3CCNC[C@@H]3c3ccc(F)cc3)c2=O)cc1 |
| Hydrogen bond acceptors | 7 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 10 |
| Molecular weight | 620.2 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | VLQGURFNWDTOFC-HAQLSYKPSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| MC5 | MC5R | Human | Melanocortin | A | pIC50 | 5.92 | 5.92 | 5.92 | ChEMBL |
| MC4 | MC4R | Human | Melanocortin | A | pIC50 | 7.18 | 7.18 | 7.18 | ChEMBL |
| MC4 | MC4R | Human | Melanocortin | A | pEC50 | 6.96 | 6.96 | 6.96 | ChEMBL |