Chembl362741


SMILES CCCCS(=O)(=O)NCc1ccc(CC(=O)N(C)[C@H](CN2CC[C@H](O)C2)c2ccccc2)cc1
InChIKey QYAKOPWJZZFMIO-LOSJGSFVSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight (Da) 487.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.78 6.78 6.78 ChEMBL
κ OPRK Human Opioid A pKi 9.1 9.1 9.1 ChEMBL
κ OPRK Human Opioid A pEC50 8.85 8.85 8.85 ChEMBL
μ OPRM Human Opioid A pKi 5.98 5.98 5.98 ChEMBL