CHEMBL3616859


SMILES CC(C)c1nnc(S[C@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@H]23)[nH]1
InChIKey INNYBEXRWKVEPM-JIUQRFSRSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 326.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.47 6.47 6.47 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.08 7.08 7.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 6.62 6.88 7.13 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 5.63 5.63 5.63 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 7.11 7.11 7.11 ChEMBL