Ligand Data

Ligand

id 1235
Name DAMGO
SMILES None
InChIKey HPZJMUBDEAMBFI-WTNAPCKOSA-N
Type peptide
Sequence YAGFG
External Links
Structure pdb 6DDE 6DDF

Structure

Properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
κ OPRK Mouse Opioid A (Rhodopsin) 4000 4000 4000
μ OPRM Mouse Opioid A (Rhodopsin) 0.8 25.9 75.5 5.0 13.5 19.0
CCK2 GASR Human Cholecystokinin A (Rhodopsin) 2.7 2.7 2.7
δ OPRD Mouse Opioid A (Rhodopsin) 950 1242 1533
δ OPRD Rat Opioid A (Rhodopsin) 180 1031 2670 49.0 49.0 49.0
κ OPRK Guinea pig Opioid A (Rhodopsin) 509 953 1841
μ OPRM Rat Opioid A (Rhodopsin) 0.5 4.7 36.3 0.3 69.6 485.0
δ OPRD Human Opioid A (Rhodopsin) 0.7 921.2 1850.0 6.9 203.4 400.0
κ OPRK Human Opioid A (Rhodopsin) 270 288 306 4000 4182 4365
μ OPRM Human Opioid A (Rhodopsin) 0.3 49.9 2187.8 0.3 54.5 378.0