CHEMBL3633656


SMILES COc1ccc(-c2[nH]c3ccccc3c2C(=O)CN(C)CC(=O)N2CCOCC2)cc1
InChIKey LRHFIHBNRRLFSM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 421.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPRC6 GPC6A Mouse C Orphans C pIC50 5.03 5.03 5.03 ChEMBL
CaS CASR Rat Calcium-sensing C pIC50 4.25 4.25 4.25 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 4.38 4.38 4.38 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pIC50 4.24 4.81 5.38 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 4.29 4.29 4.29 ChEMBL