AZAPERONE


SMILES O=C(CCCN1CCN(c2ccccn2)CC1)c1ccc(F)cc1
InChIKey XTKDAFGWCDAMPY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 327.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.92 6.93 6.94 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.17 8.18 8.2 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.81 5.84 5.87 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.05 7.12 7.28 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.2 7.27 7.34 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.09 8.11 8.12 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.64 6.77 7.28 ChEMBL
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 8.17 8.17 8.17 PDSP Ki database
D1 DRD1 Bovine Dopamine A pKi 5.77 5.77 5.77 PDSP Ki database
D2 DRD2 Bovine Dopamine A pKi 8.0 8.0 8.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database