CHEMBL365083


SMILES Fc1cc(-c2cccnc2)cc(-n2nnc(-c3ccccn3)n2)c1
InChIKey XBKXUTXPFVUGDA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 318.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.43 7.43 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.92 7.92 7.92 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.27 7.27 7.27 ChEMBL