CHEMBL346805


SMILES O=Cc1cccc2c(CN3CCN(c4ccc(Cl)cc4)CC3)cnn12
InChIKey JQJZAUBSLUYDAA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 354.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.92 5.92 5.92 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.59 8.59 8.59 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.23 5.23 5.23 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.02 5.03 5.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database