CHEMBL3663390


SMILES CCOc1ncc2ccccc2c1C(=O)N1C2CCC1C(COc1ccccn1)C2
InChIKey DQXRZOLGSQYVPN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 403.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 7.77 7.86 8.05 ChEMBL
OX1 OX1R Human Orexin A pKi 7.92 8.0 8.15 ChEMBL
OX2 OX2R Human Orexin A pKi 6.57 6.62 6.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database