CHEMBL3665720


SMILES COc1ccc([C@H](C)NC(=O)COc2cc(C)c3c(-c4cc(OC)cc(OC)c4)nn(C)c3n2)cc1
InChIKey ATDRTNDYIVXCCF-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 490.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 7.72 7.72 7.72 ChEMBL
OX2 OX2R Human Orexin A pKd 6.3 6.3 6.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database