CHEMBL3669439


SMILES O=C1N(Cc2cccc3c2OCO3)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey KJCKVHGVQQWMCK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 430.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.04 6.04 6.04 ChEMBL
OX1 OX1R Human Orexin A pKd 5.63 5.63 5.63 ChEMBL
OX2 OX2R Human Orexin A pKi 7.46 7.46 7.46 ChEMBL
OX2 OX2R Human Orexin A pKd 6.38 6.38 6.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database