CHEMBL3597585


SMILES O=C(C#Cc1ccccc1)N1CCN(c2ccccc2[N+](=O)[O-])CC1
InChIKey VNVSYPPNINVFFU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 335.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 7.16 7.16 7.16 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 8.74 8.74 8.74 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pKi 9.4 9.4 9.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database