melanin-concentrating hormone
SMILES | None |
InChIKey | ORRDHOMWDPJSNL-UHFFFAOYSA-N |
Sequence | DFDMLRCMLGRVYRPCWQV |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Endogenous/Surrogate | Endogenous |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
ETA | EDNRA | Human | Endothelin | A | pKi | 8.9 | 8.9 | 8.9 | Guide to Pharmacology |
ETA | EDNRA | Rat | Endothelin | A | pKi | 8.22 | 8.22 | 8.22 | ChEMBL |
ETB | EDNRB | Human | Endothelin | A | pKi | 6.43 | 6.43 | 6.43 | ChEMBL |
ETA | EDNRA | Human | Endothelin | A | pKi | 8.22 | 8.22 | 8.22 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
ETB | EDNRB | Human | Endothelin | A | pIC50 | 7.8 | 7.8 | 7.8 | ChEMBL |
ETA | EDNRA | Human | Endothelin | A | pIC50 | 9.1 | 9.1 | 9.1 | ChEMBL |