Difelikefalin


SMILES NCCCC[C@H](C(=O)N1CCC(CC1)(N)C(=O)O)NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)N)Cc1ccccc1)CC(C)C
InChIKey FWMNVWWHGCHHJJ-SKKKGAJSSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Surrogate
Approved drug Yes

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pEC50 10.32 10.32 10.32 Guide to Pharmacology
κ OPRK Human Opioid A pEC50 9.8 9.8 9.8 Guide to Pharmacology
κ OPRK Mouse Opioid A pEC50 10.32 10.32 10.32 ChEMBL
κ OPRK Human Opioid A pEC50 9.8 9.8 9.8 ChEMBL