methysergide


SMILES CC[C@H](NC(=O)[C@H]1CN(C)[C@H]2C(=C1)c1cccc3c1c(C2)cn3C)CO
InChIKey KPJZHOPZRAFDTN-ZRGWGRIASA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 353.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 6DRZ
Ligand site mutations 5-HT1B 5-HT2B 5-HT2C 5-HT6

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 11.9 11.9 11.9 Guide to Pharmacology
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 12.0 12.0 12.0 Guide to Pharmacology