CHEMBL3665732


SMILES COc1ccc2c(c1)CC[C@@H]2NC(=O)C(C)Oc1cc(C)c2c(C3CC3)nn(C)c2n1
InChIKey QXVOQEVRXUTGSY-PKDNWHCCSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 420.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 6.23 6.23 6.23 ChEMBL
OX2 OX2R Human Orexin A pKd 7.02 7.02 7.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database