Chembl3742429


SMILES N#CCN(CCN1CCN(c2ccc3[nH]ccc3c2Cl)CC1)[C@H]1CCc2nc(N)sc2C1
InChIKey CRIDIVQBOHLVBM-INIZCTEOSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 469.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.84 7.84 7.84 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.06 7.06 7.06 ChEMBL
D3 DRD3 Human Dopamine A pEC50 7.96 7.96 7.96 ChEMBL
D2 DRD2 Human Dopamine A pEC50 5.41 6.48 7.67 ChEMBL