CHEMBL3673025


SMILES O=C(Nc1ccc([C@@H]2CNCCO2)c(F)c1)c1ccnc(C(F)(F)F)c1
InChIKey IZKSXRNODXVURY-AWEZNQCLSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 369.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Rat Trace amine A pKi 8.12 8.12 8.12 ChEMBL
TA1 TAAR1 Mouse Trace amine A pKi 8.22 8.22 8.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database