CHEMBL3736207


SMILES COc1ccc(CCCN(CCc2ccc(OC)c(OC)c2)CCc2ccc3c(c2)OCO3)cc1
InChIKey UDHMYZKABNGRNS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 13
Molecular weight (Da) 477.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.17 8.17 8.17 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.69 6.69 6.69 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 5.4 5.4 5.4 ChEMBL