devazepide


SMILES O=C(c1cc2c([nH]1)cccc2)NC1N=C(c2ccccc2)c2c(N(C1=O)C)cccc2
InChIKey NFHRQQKPEBFUJK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 408.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK1 CCKAR Human Cholecystokinin A pKd 9.7 9.7 9.7 Guide to Pharmacology
CCK2 GASR Human Cholecystokinin A pKi 6.77 6.77 6.77 ChEMBL
CCK1 CCKAR Human Cholecystokinin A pKi 7.98 7.98 7.98 ChEMBL
CCK2 GASR Rat Cholecystokinin A pKi 6.49 8.45 9.48 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Human Cholecystokinin A pIC50 6.8 6.8 6.8 Guide to Pharmacology
CCK1 CCKAR Rat Cholecystokinin A pIC50 9.72 9.72 9.72 Guide to Pharmacology
CCK1 CCKAR Rat Cholecystokinin A pIC50 9.1 9.1 9.1 ChEMBL
CCK2 GASR Human Cholecystokinin A pIC50 6.14 6.14 6.14 ChEMBL