Chembl3770643


SMILES N[C@@H](Cc1c(Cl)cc(O)cc1Cl)C(=O)N[C@@H]1CCNc2ccc(Cc3ccccc3)cc21
InChIKey WNLHEKJUSTXAKY-LADGPHEKSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 6
Molecular weight (Da) 469.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Rat Opioid A pKi 7.43 7.43 7.43 ChEMBL
μ OPRM Rat Opioid A pEC50 7.48 7.48 7.48 ChEMBL
μ OPRM Rat Opioid A pKi 9.33 9.33 9.33 ChEMBL
κ OPRK Human Opioid A pEC50 5.92 5.92 5.92 ChEMBL
κ OPRK Human Opioid A pKi 7.46 7.46 7.46 ChEMBL