CHEMBL376700


SMILES O=C(NN1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCc1cc(Cl)ccc1-2
InChIKey NCXBPZJQQSNIRA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 488.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Mouse Cannabinoid A pKi 8.09 9.64 12.46 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 7.07 7.42 7.7 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 6.9 8.84 12.46 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 7.74 10.23 12.46 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 7.68 7.69 7.7 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database