CHEMBL376355


SMILES Nc1nc2c(s1)C[C@H]1[C@H]3Cc4ccc(O)cc4[C@@]1(CCN3CC1CCC1)C2
InChIKey LLZGBQVJBUASJT-LRXVAGHRSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 381.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.96 8.96 8.96 ChEMBL
κ OPRK Human Opioid A pKi 9.85 9.85 9.85 ChEMBL
μ OPRM Human Opioid A pKi 9.43 9.43 9.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 8.6 8.6 8.6 ChEMBL
κ OPRK Human Opioid A pIC50 7.03 7.03 7.03 ChEMBL
κ OPRK Human Opioid A pEC50 8.59 8.59 8.59 ChEMBL
μ OPRM Human Opioid A pIC50 7.58 7.58 7.58 ChEMBL
μ OPRM Human Opioid A pEC50 8.59 8.59 8.59 ChEMBL