Chembl3797228


SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCC(=O)Nc1cccc2ccccc12
InChIKey ZBEAXZAFQYRZBS-YJIIWGRFSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 414.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pEC50 5.1 5.1 5.1 ChEMBL
δ OPRD Mouse Opioid A pKd 7.6 7.6 7.6 ChEMBL
δ OPRD Rat Opioid A pKi 6.68 6.68 6.68 ChEMBL
μ OPRM Rat Opioid A pKi 7.42 7.42 7.42 ChEMBL
κ OPRK Human Opioid A pKi 6.1 6.1 6.1 ChEMBL
κ OPRK Human Opioid A pEC50 5.0 5.0 5.0 ChEMBL