CHEMBL3797209


SMILES CCCN(CCC)[C@@H]1Cc2cccc3c2n(c(=O)n3CCC)C1
InChIKey FOWVILAPRCJMGP-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 315.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 8.22 8.35 8.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.84 7.71 8.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 7.29 7.86 8.43 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.47 8.14 9.05 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.03 6.61 7.0 ChEMBL